IEDA
Project Information
Proteins of Oxygen-Binding and Energy Metabolism in Muscles of Antarctic Fishes: Evolutionary Adjustments to Life at Cold Temperature
Start Date:
2000-04-01
End Date:
2003-03-31
Description/Abstract
The suborder Notothenoidei is the dominant fish group of the Southern Ocean surrounding Antarctica, both in terms of number of species and biomass. For about fourteen million years, these highly successful fish evolved under stable thermal conditions that result in body temperatures of about zero degrees centigrade throughout their life histories. Evolution this cold environment has led to unusual physiological and biochemical characteristics. In some cases, the characteristics contribute to overcoming constraints of cold temperature on biological processes. In other instances, mutations that probably would have been lethal in warmer, less oxygen-rich environments than the Southern Ocean have been retained in Antarctic fishes. This research project focuses on three major objectives that exploit these unusual conditions to identify mechanisms compatible with normal cellular function at cold temperature and to gain unique insights into the physiological roles of key intracellular proteins. The three lines of study proposed are the molecular basis for the failure of the myoglobin encoding gene to be expressed in certain Antarctic notothenioid fishes, the basis of the substrate specificity of the enzyme fatty acyl-CoA synthetase that is involved in the catabolism of fatty acids, and the functional roles played by different isoforms of creatine phosphokinase in locomotory muscle of Antarctic fish. Results from this study will not only provide insight into the evolutionary biology of the Antarctic notothenioid fishes, but will elucidate important general principles that are applicable to widely different taxa beyond the Antarctic.
Personnel
Person Role
Sidell, Bruce Investigator
Funding
Antarctic Organisms and Ecosystems Award # 9909055
AMD - DIF Record(s)
Deployment
Deployment Type
LMG0105 ship expedition
Data Management Plan
None in the Database
Product Level:
Not provided
Datasets
Repository Title (link) Format(s) Status
R2R Expedition data of LMG0105 None exists
R2R Expedition Data None exist
Platforms and Instruments

This project has been viewed 3 times since May 2019 (based on unique date-IP combinations)