USAP-DC

[{"dataset_id": "600118", "west": 166.66667, "east": 166.66667, "south": -77.83333, "north": -77.83333, "gid": 319, "geometry": "0101000020E61000002EE7525C55D56440A5315A47557553C0", "cross_dateline": false, "bounds_geometry": "0101000020E61000002EE7525C55D56440A5315A47557553C0"}]

{"@context": "https://schema.org/", "@type": "Dataset", "@id": "doi:10.15784/600118", "additionalType": ["geolink:Dataset", "vivo:Dataset"], "name": "The Cellular Stress Response in Cold-adapted Organisms: Building Novel Mechanistic Links between Heat Stress, Cell Cycle Arrest and Apoptosis in Antarctic Fishes.", "description": "The research will investigate a novel mechanism by which cold-adapted fishes of the Southern Ocean sense and respond to elevated temperatures. It is hypothesized that sub-lethal heat stress may induce cell cycle arrest and/or programmed cell death through apoptosis. The study will use genome-enabled technologies to examine the environmental control over gene expression in Antarctic species and will build direct mechanistic links between the expression of a specific signaling pathway gene and heat-induced changes in cells. Prior results support the hypothesis that heat stress results in cell cycle arrest and, in some cases, programmed cell death in Antarctic fishes. If so, this represents a novel, modified version of the well-conserved cellular stress response found in essentially all other species and suggests that warming ocean temperatures may have profound cellular and physiological impacts on these extremely stenothermal species. The P.I. conducts outreach activities with the Oregon Museum of Science and Industry, will be involved in developing a science curriculum for the Native American Youth and Family Center (NAYA) Early College Academy in Portland, and supports the educational and professional development of both undergraduate and graduate students at Portland State University.\n", "citation": "Buckley, B. (2013) \"The Cellular Stress Response in Cold-adapted Organisms: Building Novel Mechanistic Links between Heat Stress, Cell Cycle Arrest and Apoptosis in Antarctic Fishes.\" U.S. Antarctic Program (USAP) Data Center. doi: https://doi.org/10.15784/600118.", "datePublished": "2013", "keywords": ["Biota", "Biota", "Southern Ocean"], "creator": [{"@type": "Person", "additionalType": "geolink:Person", "name": "Buckley, Bradley", "email": "bbuckley@pdx.edu", "affiliation": {"@type": "Organization", "name": "Portland State University"}}], "distribution": [{"@type": "DataDownload", "additionalType": "http://www.w3.org/ns/dcat#DataCatalog", "encodingFormat": "text/xml", "name": "ISO Metadata Document", "url": "https://www.usap-dc.org/metadata/isoxml/600118iso.xml", "contentUrl": "/dataset/filename"}, {"@type": "DataDownload", "@id": "http://dx.doi.org/10.15784/600118", "additionalType": "dcat:distribution", "url": "http://dx.doi.org/10.15784/600118", "name": "landing page", "description": "Link to a web page related to the resource.. Service Protocol: Link to a web page related to the resource.. Link Function: information", "contentUrl": "/dataset/filename", "encodingFormat": "text/html"}, {"@type": "DataDownload", "@id": "https://www.usap-dc.org/view/dataset/600118", "additionalType": "dcat:distribution", "url": "https://www.usap-dc.org/view/dataset/600118", "name": "landing page", "description": "Link to a web page related to the resource.. Service Protocol: Link to a web page related to the resource.. Link Function: information", "contentUrl": "/dataset/filename", "encodingFormat": "text/html"}], "identifier": {"@type": "PropertyValue", "propertyID": "https://registry.identifiers.org/registry/doi", "value": "doi:10.15784/600118", "url": "https://doi.org/10.15784/600118"}, "contributor": [{"@type": "Role", "roleName": "credit", "description": "funderName:NSF:GEO:PLR:Antarctic Organisms and Ecosystems awardNumber:0944743 awardTitle:The Cellular Stress Response in Cold-adapted Organisms: Building Novel Mechanistic Links between Heat Stress, Cell Cycle Arrest and Apoptosis in Antarctic Fishes."}], "license": [{"@type": "CreativeWork", "URL": "https://creativecommons.org/licenses/by-nc/4.0/", "name": "MD_Constraints", "description": "useLimitation: Creative Commons Attribution-NonCommercial v4.0 Generic [CC BY-NC 4.0]."}, {"@type": "CreativeWork", "name": "MD_LegalConstraints", "description": "accessConstraints: license. otherConstraints: Creative Commons Attribution-NonCommercial v4.0 Generic [CC BY-NC 4.0]."}, {"@type": "CreativeWork", "name": "MD_SecurityConstraints", "description": "classification: "}], "publisher": {"@type": "Organization", "name": "U.S. Antarctic Program (USAP) Data Center"}, "spatialCoverage": [{"@type": "Place", "geo": {"@type": "GeoCoordinates", "longitude": 166.66667, "latitude": -77.83333}}]}

The Cellular Stress Response in Cold-adapted Organisms: Building Novel Mechanistic Links between Heat Stress, Cell Cycle Arrest and Apoptosis in Antarctic Fishes. Data DOI: https://doi.org/10.15784/600118 Cite as Buckley, B. (2013) "The Cellular Stress Response in Cold-adapted Organisms: Building Novel Mechanistic Links between Heat Stress, Cell Cycle Arrest and Apoptosis in Antarctic Fishes." U.S. Antarctic Program (USAP) Data Center. doi: https://doi.org/10.15784/600118. AMD - DIF Record(s) NSF-ANT09-44743_1 Abstract The research will investigate a novel mechanism by which cold-adapted fishes of the Southern Ocean sense and respond to elevated temperatures. It is hypothesized that sub-lethal heat stress may induce cell cycle arrest and/or programmed cell death through apoptosis. The study will use genome-enabled technologies to examine the environmental control over gene expression in Antarctic species and will build direct mechanistic links between the expression of a specific signaling pathway gene and heat-induced changes in cells. Prior results support the hypothesis that heat stress results in cell cycle arrest and, in some cases, programmed cell death in Antarctic fishes. If so, this represents a novel, modified version of the well-conserved cellular stress response found in essentially all other species and suggests that warming ocean temperatures may have profound cellular and physiological impacts on these extremely stenothermal species. The P.I. conducts outreach activities with the Oregon Museum of Science and Industry, will be involved in developing a science curriculum for the Native American Youth and Family Center (NAYA) Early College Academy in Portland, and supports the educational and professional development of both undergraduate and graduate students at Portland State University. Creator(s): Buckley, Bradley Date Created: 2013-01-01 Repository: USAP-DC (current) - LDEO-LEGACY (original) License: Creative Commons Attribution-NonCommercial v4.0 Generic [CC BY-NC 4.0] Spatial Extent(s) West: 166.66667, East: 166.66667, South: -77.83333, North: -77.83333 Temporal Extent(s) Start: 2010-08-15 - End: 2013-07-31 Award(s) NSF 0944743 Version: 1 Related Project(s) The Cellular Stress Response in Cold-adapted Organisms: Building Novel Mechanistic Links between Heat Stress, Cell Cycle Arrest and Apoptosis in Antarctic Fishes. Keywords Biota Biota Southern Ocean