[{"awards": "1341663 O\u0027Brien, Kristin; 1341602 Crockett, Elizabeth", "bounds_geometry": null, "date_created": "Fri, 18 Dec 2020 00:00:00 GMT", "description": "Icefishes characteristically lack the oxygen-binding protein haemoglobin and therefore are especially reliant on cardiovascular regulation to augment oxygen transport when oxygen demand increases, such as during activity and warming. Using both in vivo and in vitro experiments, we evaluated the roles for adrenaline and adenosine, two well-established cardio- and vasoactive molecules, in regulating the cardiovascular system of the blackfin icefish, Chaenocephalus aceratus. Despite increasing cardiac contractility (increasing twitch force and contraction kinetics in isometric myocardial strip preparations) and accelerating heart rate (\u0192H), adrenaline (5 nmol kg-1 bolus intra-arterial injection) did not significantly increase cardiac output (Q\u0307) in vivo because it elicited a large decrease in vascular conductance (Gsys). In contrast, and despite preliminary data suggesting a direct negative inotropic effect of adenosine on isolated atria and little effect on isolated ventricle strips, adenosine (500 nmol kg-1) generated a large increase in Q\u0307 by increasing Gsys, a change reminiscent of that previously reported during both acute warming and invoked activity. Our data thus illustrate how Q\u0307 in C. aceratus may be much more dependent on peripheral control of vasomotor tone than direct regulation of the heart. ", "east": null, "geometry": null, "keywords": "Antarctica; Antarctic Peninsula", "locations": "Antarctic Peninsula; Antarctica", "north": null, "nsf_funding_programs": "Antarctic Organisms and Ecosystems; Antarctic Organisms and Ecosystems", "persons": "Joyce, Michael; Axelsson, Michael; Farrell, Anthony; Egginton, Stuart; O\u0027Brien, Kristin", "project_titles": "Collaborative Research: The Physiological and Biochemical Underpinnings of Thermal Tolerance in Antarctic Notothenioid Fishes", "projects": [{"proj_uid": "p0010084", "repository": "USAP-DC", "title": "Collaborative Research: The Physiological and Biochemical Underpinnings of Thermal Tolerance in Antarctic Notothenioid Fishes"}], "repo": "USAP-DC", "repositories": "USAP-DC", "science_programs": null, "south": null, "title": "Adrenergic and adenosinergic regulation of the cardiovascular system in the Antarctic icefish Chaenocephalus aceratus", "uid": "601409", "west": null}, {"awards": "0944193 MacAyeal, Douglas", "bounds_geometry": ["POLYGON((-88 42,-87.9 42,-87.8 42,-87.7 42,-87.6 42,-87.5 42,-87.4 42,-87.3 42,-87.2 42,-87.1 42,-87 42,-87 41.9,-87 41.8,-87 41.7,-87 41.6,-87 41.5,-87 41.4,-87 41.3,-87 41.2,-87 41.1,-87 41,-87.1 41,-87.2 41,-87.3 41,-87.4 41,-87.5 41,-87.6 41,-87.7 41,-87.8 41,-87.9 41,-88 41,-88 41.1,-88 41.2,-88 41.3,-88 41.4,-88 41.5,-88 41.6,-88 41.7,-88 41.8,-88 41.9,-88 42))"], "date_created": "Mon, 25 Aug 2014 00:00:00 GMT", "description": "This data set represents a typical single iceberg capsize experiment. Included in this data set are all the parameters of the plastic iceberg\u0027s density and dimensions, the density of the water surrounding the iceberg, and the value of gravitational acceleration. The timeseries data consists of all the kinematic and energetic variables as a function of time for the iceberg capsize experiment.", "east": -87.0, "geometry": ["POINT(-87.5 41.5)"], "keywords": "Antarctica; Glaciology; Iceberg; Kinetics", "locations": "Antarctica", "north": 42.0, "nsf_funding_programs": "Antarctic Glaciology", "persons": "MacAyeal, Douglas", "project_titles": "Collaborative Research: Explosive Ice-Shelf Disintegration", "projects": [{"proj_uid": "p0000005", "repository": "USAP-DC", "title": "Collaborative Research: Explosive Ice-Shelf Disintegration"}], "repo": "USAP-DC", "repositories": "USAP-DC", "science_programs": null, "south": 41.0, "title": "Iceberg Capsize Kinematics and Energetics", "uid": "609590", "west": -88.0}]

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Dataset Title/Abstract/Map	NSF Award(s)	Date Created	PIs / Scientists	Project Links	Abstract	Bounds Geometry	Geometry	Selected	Visible
Adrenergic and adenosinergic regulation of the cardiovascular system in the Antarctic icefish Chaenocephalus aceratus	1341663 1341602	2020-12-18	Joyce, Michael; Axelsson, Michael; Farrell, Anthony; Egginton, Stuart; O'Brien, Kristin	Collaborative Research: The Physiological and Biochemical Underpinnings of Thermal Tolerance in Antarctic Notothenioid Fishes	Icefishes characteristically lack the oxygen-binding protein haemoglobin and therefore are especially reliant on cardiovascular regulation to augment oxygen transport when oxygen demand increases, such as during activity and warming. Using both in vivo and in vitro experiments, we evaluated the roles for adrenaline and adenosine, two well-established cardio- and vasoactive molecules, in regulating the cardiovascular system of the blackfin icefish, Chaenocephalus aceratus. Despite increasing cardiac contractility (increasing twitch force and contraction kinetics in isometric myocardial strip preparations) and accelerating heart rate (ƒH), adrenaline (5 nmol kg-1 bolus intra-arterial injection) did not significantly increase cardiac output (Q̇) in vivo because it elicited a large decrease in vascular conductance (Gsys). In contrast, and despite preliminary data suggesting a direct negative inotropic effect of adenosine on isolated atria and little effect on isolated ventricle strips, adenosine (500 nmol kg-1) generated a large increase in Q̇ by increasing Gsys, a change reminiscent of that previously reported during both acute warming and invoked activity. Our data thus illustrate how Q̇ in C. aceratus may be much more dependent on peripheral control of vasomotor tone than direct regulation of the heart.	[]	[]	false	false
Iceberg Capsize Kinematics and Energetics	0944193	2014-08-25	MacAyeal, Douglas	Collaborative Research: Explosive Ice-Shelf Disintegration	This data set represents a typical single iceberg capsize experiment. Included in this data set are all the parameters of the plastic iceberg's density and dimensions, the density of the water surrounding the iceberg, and the value of gravitational acceleration. The timeseries data consists of all the kinematic and energetic variables as a function of time for the iceberg capsize experiment.	["POLYGON((-88 42,-87.9 42,-87.8 42,-87.7 42,-87.6 42,-87.5 42,-87.4 42,-87.3 42,-87.2 42,-87.1 42,-87 42,-87 41.9,-87 41.8,-87 41.7,-87 41.6,-87 41.5,-87 41.4,-87 41.3,-87 41.2,-87 41.1,-87 41,-87.1 41,-87.2 41,-87.3 41,-87.4 41,-87.5 41,-87.6 41,-87.7 41,-87.8 41,-87.9 41,-88 41,-88 41.1,-88 41.2,-88 41.3,-88 41.4,-88 41.5,-88 41.6,-88 41.7,-88 41.8,-88 41.9,-88 42))"]	["POINT(-87.5 41.5)"]	false	false

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